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    • PATAS, a first-in-class therapeutic peptide biologic, improves whole-body insulin resistance and associated comorbidities in vivo

      Schreyer E, Obringer C, Messaddeq N, Kieffer B, Zimmet P, Fleming A, Geberhiwot T, Marion V


      Diabetes

      2022 ; 71 : 1–14.

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    • Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance

      Geberhiwot T, Baig S, Obringer C, Girard D, Dawson C, Manolopoulos K, Messaddeq N, Bel Lassen P, Clement K, Tomlinson J W, Steeds R P, Dollfus H, Petrovsky N, Marion V 


      Diabetes

      2021 ; 70 : 364–376.

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    • 147-LB: PATAS, an Adipocyte-Targeted Peptide Approach to Treat Type 2 Diabetes and Associated Comorbidities

      Marion V


      Diabetes

      2019 ; 68 : 147-LB.

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    • BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response

      Marion V, Mockel A, De Melo C, Obringer C, Claussmann A, Simon A, Messaddeq N, Durand M, Dupuis L, Loeffler J-P, King P, Mutter-Schmidt C, Petrovsky N, Stoetzel C, Dollfus H


      Cell Metabolism 

      2012 ; 16 : 363–377.

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    • Transient ciliogenesis involving Bardet-Biedl syndrome proteins is a fundamental characteristic of adipogenic differentiation

      Marion V, Stoetzel C, Schlicht D, Messaddeq N, Koch M, Flori E, Danse J-M, Mandel J-L, Dollfus H


      Proc Natl Acad Sci U S A 

      2009 ; 106 : 1820–1825.

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